IgA nephropathy may lead to complications such as high blood pressure, swelling, anemia, and reduced kidney function. Managing these issues is a vital part of treatment.
Hypertension is managed with medications and lifestyle changes. Swelling is addressed through diuretics and fluid management.
Complications like anemia require iron supplements or hormone therapy to improve energy and prevent fatigue. Bone health may also be affected due to phosphorus imbalance, requiring nutritional adjustments.
Managing complications helps stabilize kidney function and improves everyday life for patients.
The cornerstone of management remains optimal control of blood pressure and proteinuria. Physicians commonly prescribe renin-angiotensin-aldosterone system inhibitors to protect the kidneys by lowering pressure within the glomeruli. Many patients also benefit from lifestyle adjustments such as reduced salt intake, smoking cessation, and regular physical activity. These steps, while simple, have meaningful long-term impact by reducing stress on damaged kidneys.
Immunosuppressive therapies continue to play a role for select patients who experience rapid renal decline or severe inflammation. Corticosteroids have been used for decades, although their side effects require careful consideration. More targeted medications, such as those modulating B-cell activity or complement pathways, are emerging as promising alternatives. These therapies aim to reduce the autoimmune response without exposing patients to the systemic impact of traditional immunosuppression.
Supportive care remains equally important. Patients often need guidance on managing fatigue, dietary restrictions, and the emotional stress associated with chronic disease. Multidisciplinary teams—including nephrologists, dietitians, and mental-health professionals—help patients navigate the physical and psychological challenges of living with a lifelong condition.